Gerben Vader – Principal investigator

Research interests
The research in my group is centered around the effects of aberrant expression of normally meiosis-specific genes on DNA repair dysfunction and/or re-wiring in cancer. We are interested in understanding how cancer cells exploit idiosyncratic DNA repair pathways and functionalities that normally act in meiosis. We employ a combination of state-of-the-art genetics, cell biology and cancer biology to define how these pathways might represent currently underexplored potential avenues for biomarker development and therapeutic intervention.